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Complement System Pathways
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12:45
YouTube
Joe DeMasi
Alternative pathway of complement activation
This video introduces the alternative pathway of complement activation, covering how the pathogen is recognized by complement proteins, leading to the formation of both the soluble C3 convertase and and alternative C3 convertase.
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✨Complement Coagulation Pathway✨ 🔸Interconnection between two major plasma cascade systems in the body: the Complement system (innate immunity) and the Coagulation system (blood clotting). 💐Complement Pathway💐 3 activation routes, all converging at the formation of C3 convertase → C5 convertase → Membrane Attack Complex (MAC, C5b–9): 🔸1.Classical pathway → triggered by Ag–Ab complexes (IgG, IgM) 🔸2.Lectin pathway → triggered by Mannose-binding lectin (MBL) 🔸3.Alternative pathway → triggere
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