Advancements in spatial perturbation transcriptomics (SPT) have revolutionized our understanding of cellular behavior in native tissue contexts by integrating spatial and perturbation data. However, ...
aDepartment of Genetic and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA bDivision of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, ...
1Department of Physiology, Ajou University School of Medicine, Suwon, Korea, Rep.
Abstract: Spatial transcriptomics has revolutionized the ability to investigate transcriptional patterns within tissue morphology. However, many ST clustering pipelines operate on a single preselected ...
A new software tool, ovrlpy, improves quality control in spatial transcriptomics, a key technology in biomedical research. Developed by the Berlin Institute of Health at Charité (BIH) in international ...
Graph Convolutional Networks (GCNs) are widely applied for spatial domain identification in spatial transcriptomics (ST), where node representations are learned by aggregating information from ...
Spatial omics is a new generation of technologies that allow scientists to study cells in their original location within tissues (without isolating or moving them from their environment). Just as a ...
Gastric cancer (GC) develops through a sequence from chronic gastritis to intestinal metaplasia (IM) and carcinoma, with Helicobacter pylori (HP) as a key driver; however, the molecular mediators ...
Abstract: Recent advancements in spatial transcriptomics technology have enabled the capture of gene expression profiles while maintaining spatial information. Accurately identifying spatial ...
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