Introduction Fertility patients increasingly use web-based and mobile-based apps to access psychosocial care. These digital tools may be a helpful alternative to traditional psychological ...

An adaptive model for developing guidelines is needed to ensure recommendations are actionable and timely Guidelines should help clinicians and patients make better decisions, but too often they do ...

The UK government’s latest grab for patient data is happening at the worst possible time. The scandal of the UK Biobank data leak is still unfolding, with medical details from half a million patients ...

Endovascular resuscitation (EVR) describes a collection of novel therapies that aim to bridge patients in shock states or cardiac arrest to definitive treatment, through a combination of haemorrhage ...

Pharmacotherapy for obstructive sleep apnoea (OSA) has entered a new phase in which the focus is shifting from broad, one-size-fits-all approaches to targeted treatments matched to specific ...

Background The association between change in high-sensitivity cardiac troponin T (hs-cTnT) and stroke risk in the general population remains unknown. We aimed to assess the association of a 6-year ...

Sepsis is a life-threatening syndrome driven by a dysregulated host response to infection. Immune dysregulation arises from responses that initially were activated to protect against pathogens and ...

Background Super large bore aspiration catheters (SLACs; inner diameter ≥0.080 inch) have been introduced to enhance efficacy in mechanical thrombectomy for large vessel occlusion (LVO). Although ...

Adult health inequalities are a persistent public health problem. Explanations are usually sought in behaviours and environments in adulthood, despite evidence on the importance of early life ...

Inflammatory bowel disease (IBD) is typically diagnosed after the onset of symptoms in the context of established, characteristic patterns of intestinal inflammation. However, there is now substantial ...

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Multiligament knee injuries (MLKIs) represent a broad spectrum of pathology with potentially devastating consequences. Currently, disagreement in the terminology, diagnosis and treatment of these ...