Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

The authors of this manuscript study the transcriptional regulators that allow macrophages to assume different functional phenotypes in response to immune stimuli. They generate a computational map of ...

ABSTRACT: Osteoarthritis (OA) is a degenerative joint disease that is common and significantly impacted in middle-aged and elderly people, and its accompanying inflammatory response plays a crucial ...

The M1 Carbine is one of the most recognizable and long-serving military firearms in the world. Though many consider it to be the anemic kid brother of the legendary M1 Garand, the carbine has its own ...

A recent study reveals that dimethyl fumarate (DMF), a compound already approved for other inflammatory diseases, can prevent and alleviate periodontal tissue damage. The research demonstrates that ...

A recent study reveals that dimethyl fumarate (DMF), a compound already approved for other inflammatory diseases, can prevent and alleviate periodontal tissue damage. The research demonstrates that ...

Macrophages are ubiquitous innate immune cells found in almost every organ of the body. This family of phagocytes, represented by a variety of different subtypes, performs tissue-specific functions as ...

1 School of Pharmaceutical Sciences, Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming, China. 2 Yunnan College of Modern Biomedical Industry, Kunming Medical University, Kunming, ...

The following is a summary of “Signaling lymphocytic activation molecule family 8 disrupts epithelial barrier in chronic rhinosinusitis with nasal polyps through M1 macrophage polarization,” published ...