The complement system is an innate immune response that leads to increased inflammation. The drug pegcetacoplan—a complement inhibitor—was approved for medical use in the United States in 2021 to ...

Novo Nordisk is paying $240 million for global rights to a Phase 3-ready drug from Omeros that could rival immune disorder medications currently available from companies such as AstraZeneca, Novartis, ...

Robert F. Kennedy Jr.’s warning about mitochondria slipped in between the anti-vaccine junk science and the excoriation of pharmaceutical drugs as “the No. 3 killer in our country.” He was speaking in ...

Booleans may seem harmless, but using them can be fraught with peril. When you can’t avoid them, follow these five rules. Booleans are deceptively simple. They look harmless—just true or false, right?

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

Results from late-stage clinical trials suggest the GLP-1 pill orforglipron could be a promising alternative to injectable GLP-1 drugs like Ozempic. A late-stage clinical trial showed a new daily ...

SAN ANTONIO — More than half of patients with pretreated HER2-positive advanced or metastatic breast cancer who received the antibody-drug conjugate trastuzumab deruxtecan (T-DXd; Enhertu) had ...

--Participant baseline characteristics in INFRONT-3 suggest a representative study population that enables testing of the effects of latozinemab in frontotemporal dementia with a progranulin gene ...

Your heart is a muscular organ that helps circulate your blood, which delivers oxygen and nutrients to your tissues. There are four chambers and four valves in your heart, and each ensures proper ...

These findings suggest complement protein levels may be an important biomarker for type 1 diabetes. Disruption of the complement system appears to precede the onset of islet autoimmunity (IA), making ...