A few hours before kickoff Sunday morning the 49ers downgraded quarterback Brock Purdy and wide receiver Jauan Jennings to out for the team's home opener. Both players were listed as questionable.

The San Francisco 49ers and Arizona Cardinals are set to kick off on Sunday, and they'll be without a few players, who have been deemed inactive.

Expert picks are a little more split than they were in Week 2 when the 49ers took on the rebuilding New Orleans Saints. We're leaning toward the Cardinals in Week 3 since it appears the teams are ...

San Francisco 49ers wide receiver Jauan Jennings is questionable to suit up in Week 3 vs. the Arizona Cardinals. Here's the latest on his injuries.

The San Francisco 49ers and Arizona Cardinals will meet on Sunday for an NFC West battle in Week 3. Here's what fans should know before the game.

The San Francisco 49ers and Arizona Cardinals will meet on Sunday. Here's what fantasy owners should do with their 49ers in Week 3.

The San Francisco 49ers have had a tough time with the Arizona Cardinals since head coach Kyle Shanahan took over in the 2017 season.

Head coach Kyle Shanahan on Friday told reporters new starting left guard Connor Colby suffered a groin injury that will make him questionable for the 49ers' home opener Sunday vs. the Arizona ...

The San Francisco 49ers could completely flip their QB depth chart with Brock Purdy working through a toe injury.

The San Francisco 49ers may have lost starting offensive lineman Ben Bartch early in their Week 2 matchup against the New ...

The San Francisco 49ers will begin Week 3 with even more injury questions than they had lingering into Week 2.

Brown, a third-round pick and the 49ers' first selection in the 2023 draft, was moved to the bench after starting 13 of the ...