They were hardly modest, these two brash young scientists who in 1953 declared to patrons of the Eagle Pub in Cambridge, England, that they had "found the secret of life." But James Watson and Francis ...

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Red arrows indicate the nuclear spin axes at the positions of the N3 nitrogen atoms on the guanine (G) bases. Due to the helical structure of DNA, there is an angular deviation in the orientation of ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

James Watson, one of the 20th century’s most famous scientists, passed away on Thursday (November 6). He was 97. Despite this, Watson was supportive of female scientists, shared Nancy Hopkins, a ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

James D. Watson, the brilliant but controversial American biologist whose 1953 discovery of the structure of DNA, the molecule of heredity, ushered in the age of genetics and provided the foundation ...

Before Watson and Crick basked in Nobel glory, before The Double Helix mythologized their genius, there was the photo. Photo 51 — crisp, clear, and groundbreaking — captured by Dr. Rosalind Franklin, ...