The rate of evolution varies among sites within proteins owing to structural and functional constraints. The main pattern of variation is due to structural constraints: evolutionary rates increase ...

OBJECTIVES: Clinical practice guidelines recommend at least annual testing of estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (uACR) for patients with chronic kidney ...

Gain-of-function research (GOFR) refers to the serial passaging of microorganisms to increase their transmissibility, virulence, immunogenicity, and host tropism by applying selective pressure to a ...

Aortic stenosis is a narrowing of the aortic valve, which connects the heart to the rest of the body. It affects millions of ...

This is a preview. Log in through your library . Abstract Traditional sensitivity analysis of linear programming objective function coefficients concerns itself with variations in single parameters.

President Trump issued an executive order Monday restricting federal funding for research that involves a controversial field of scientific study known as "gain-of-function" research. The research, ...