Figure 1: Characteristic drug responses of resistance, tolerance and persistence. Experimental discrimination between the different strategies used by bacterial cells for survival during exposure to ...

Disease tolerance is an evolutionarily conserved defence strategy against infection that does not exert a direct negative effect on the host pathogen load. Disease tolerance relies on tissue damage ...

The concept of the Window of Tolerance was developed by Dr. Dan Siegel, a clinical professor of psychiatry, to describe the ...

The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...