A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a ...

A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a ...

How do tertiary lymphoid structures influence immunotherapy outcomes in Merkel cell carcinoma? Spatial proteomics reveals key insights. Read more.

TLSs are highly organized structures that typically appear as clusters of B-cells containing FDCs. These clusters are then surrounded by T-cells and HEVs as shown schematically in Figure 1. We ...

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell ...

Researchers at Moffitt Cancer Center have developed a novel biomaterial-based system that induces the formation of tertiary lymphoid-like structures (TLSs). These immune cell clusters are increasingly ...

Researchers have identified how to encourage tumors to build their own immune hubs—structures that look and function like lymph nodes—deep in the middle of cancer. Such immune hubs, known as tertiary ...

A team led by surgeon-scientist Dr. Vinod Balachandran identified the molecular pathway involved in the formation of tertiary lymphoid structures. Therapeutically targeting this pathway could ...

Retrospective validation of a novel multimodal AI prognostic tool integrating digital pathology and clinical data against real world data and Oncotype DX in a Swiss breast cancer cohort. This is an ...

BORDEAUX, France--(BUSINESS WIRE)--TreeFrog Therapeutics has announced a research collaboration with the University of Pittsburgh focused on the potential of tertiary lymphoid structures (TLS) in ...