In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...
The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...
DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.
Support cells surrounding stem cells rather than stem cells alone, are far more vulnerable to ageing and may hold the key to understanding how tissues age and lose their generative capacity.