Stem cells are the original cell type from which all other cells and tissues in the body develop through a very tightly regulated process. However, how stem cells differentiate in addition to ...

Researchers from The University of Osaka found that the zinc finger proteins RLF and ZFP292 play redundant roles in ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Years before he conducted the research that would earn him a Nobel Prize in Physiology and Medicine, Shinya Yamanaka, MD, Ph.D., was a postdoctoral scientist at Gladstone Institutes, studying genes.

Researchers from the Hebrew University of Jerusalem and the Weizmann Institute of Science have identified a previously ...

Multi-day gene activity profiles from the same cells • Long-term analysis of cell communication in mixed cultures • Potential applications in organoids and tumor microenvironments Until now, studying ...

GC Therapeutics (GCTx), a pioneering biotechnology company advancing the next generation of cell-based medicines through its ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

One of the biggest obstacles in mesenchymal stem cell (MSC) therapy is not obtaining the cells, but ensuring that they perform effectively after transplantation. Although MSCs are widely valued for ...

Egg whites may be perfect for a health-conscious breakfast, but egg yolks turned out to be the key ingredient for cultivating bird embryonic stem cells (ESCs) in the lab. Using a growing medium of egg ...