Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...
DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...
For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...
Researchers show that loss of the SPRTN enzyme lets DNA–protein crosslinks accumulate, leak DNA into the cytoplasm, activate ...
Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...
A research team has identified a new mechanism that controls DNA’s ability to replicate—and thereby a cell’s ability to ...
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Unusual i-DNA structure shown to regulate genes and cancer
DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...
A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.
DNA’s iconic double helix does more than “just” store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...
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