Background The role of mineralocorticoid receptor antagonists (MRAs) in acute myocardial infarction (MI) remains ...

Objective To perform a large-scale pairwise and network meta-analysis on the effects of all relevant exercise training modes on resting blood pressure to establish optimal antihypertensive exercise ...

The study addresses a critical clinical question, as patients with type 2 diabetes mellitus (T2DM) face a substantially ...

Design Systematic review with random effects meta-analysis and meta-regression. Data sources Online databases up to 12 January 2024, reference lists, recommended studies and hand searches. Eligibility ...

Phase I dose-finding studies aim at identifying the maximum tolerated dose (MTD). Often, several dose-finding studies are conducted with some variation in the administration mode or dose panel. For ...

Meta-analysis is an objective examination of published data from many studies of the same research topic identified through a literature search. Through the use of rigorous statistical methods, it can ...