Researchers from the National University of Singapore (NUS) have developed CellScope, a high-performance single-cell analysis ...

This is not incremental progress - it is a step-change that unlocks industrial-scale biology for drug discovery, toxicology, and AI-driven research. Our additional investment reflects our conviction ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Researchers in China developed toGC, a new tool that corrects errors in gene annotations using RNA-seq data. Experimentally validated toGC's accuracy, discovering two novel GPCR genes misannotated as ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

In the quest for RNA biomarkers indicative of fruit maturity, a cost-effective, reliable workflow is crucial. Accurate harvest timing is critical for shelf life and apple quality, but at present, ...

In RNA-seq library preparation, selecting the appropriate number of PCR cycles is a critical balancing act to avoid overcycling.

A secondary stress signaling pathway in the response to optic axon injury is an unexpectedly strong contributor to both neurodegeneration and axon regenerative potential.

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...