DNA copy number represents an essential parameter in the dynamics of synthetic gene circuits but typically is not explicitly considered. A new study demonstrates how dynamic control of DNA copy number ...

DNA vaccines, wherein a new antigen is inserted into a validated vector, have tremendous potential for deployment in pandemic applications as they can be rapidly produced in a validated, ...

Bacterial cells often possess molecules of closed, circular DNA, otherwise known as ‘plasmids’. They can also be present at much lower frequencies in certain eukaryotic cell types, such as yeast. They ...