The permeability of biological membranes is a key determinant of drug pharmacokinetics. Historically, passive diffusion through the lipid bilayer portion of a biological membrane was suggested as the ...

The outer membrane (OM) of gram-negative bacteria forms a protective layer around the cell that serves as a permeability barrier to prevent unrestricted access of noxious substances. The permeability ...

Bacteria and yeast need to prevent leakage of numerous small molecules through their cell membrane. Biochemists have studied how the composition of the membrane affects passive diffusion and the ...

Impact of dose density of adjuvant chemotherapy for locally advanced urothelial cancer. Background: Device-assisted intravesical mitomycin-C (MMC), including electromotive administration (EMDA) and ...

Passive diffusion plays an essential role in oral absorption of drugs through the gastrointestinal tract, penetration across the blood-brain barrier to reach Central Nervous System disease targets, ...

Cells continuously move materials in and out through their cell walls. Facilitated transport is one way of moving those materials without expending cellular energy. In facilitated transport, materials ...