Onchocerciasis, also known as "river blindness", is a neglected tropical disease infecting millions of people mainly in Africa and the Middle East but also in South America and Central America.

Despite decades of research, scientists have yet to pinpoint the exact cause of nodding syndrome (NS), a disabling disease affecting African children. A new report suggests that blackflies infected ...

Previous ultrastructural studies on various microfilariae have suggested the presence of a trilaminar membrane at the parasite cuticle. In the present report, the formation of the cuticle of ...

Scientists have for the first time fully sequenced the genome of onchocerca volvulus, the parasitic worm that causes river blindness. This has allowed them to identify a number of proteins that could ...

Recent reports of patients failing to respond to ivermectin, the standard drug for treating river blindness (onchocerciasis), have suggested the emergence of drug-resistant Onchocerca volvulus (the ...

River blindness is a common chronic infectious neglected disease that blights many communities near water in remote areas of the Amazon basin in South America and in Africa. It is caused by the worm ...

Moxidectin, a macrocyclic lactone, is an anthelmintic drug that selectively binds to the parasite's glutamate-gated chloride ion channels. The Food and Drug Administration (FDA) has approved ...

The debilitating parasitic disease, onchocerciasis, is all but vanquished in one corner of Sudan, thanks to a community-wide health effort. A series of rodent experiments showed that even with ...