Nucleotide excision repair (NER) is a major conserved DNA repair pathway, which repairs various types of damage in the genome, such as those induced by ultraviolet light and environmental agents.

Researchers decode repair mechanism during transcription of genetic information. Cockayne syndrome is a severe autosomal recessive disorder caused by defective DNA repair mechanisms. People with the ...

Ananthaswamy HN, Ouhtit A, Evans RL, Gorny A, Kashkina P, Sands AT and Conti CJ. . 1999 Oncogene 18: 7395–7398. Berg RJW, Rebel HG, Van der Horst GTJ, Mullenders LHF, Van Vloten WA and De Gruijl FR. .

Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions. The key steps in the NER ...

Polymorphisms in epidermal growth factor (EGF) and proteinase activated receptor 1 (PAR-1) associated with tumor recurrence in localized adenocarcinoma (EA) of the esophagus treated with surgery alone ...

Impact of next-generation sequencing (NGS) on the diagnosis of gliomas according to the WHO-2016 and WHO-2021 classification in routine clinical practice. This is an ASCO Meeting Abstract from the ...