Overview of the study. Researchers investigated the neural basis of how animals adapt to new environments and situations. To do this, they introduced a chemical ON/OFF switch in the orbitofrontal ...

Across the entire animal kingdom, visual images are processed by two major neuronal pathways that extract light and dark stimuli from visual scenes – ON (light on) and OFF (light off) pathways. Light ...

Quick-acting targeted therapies with minimal side effects are an urgent need for the treatment of anxiety-related disorders. While delta opioid receptor (DOP) agonists have shown 'anxiolytic' or ...

Neuronal pathways originating from the orbitofrontal cortex (OFC) of the brain participate in different adaptive behaviors, but which pathways are used for distinct adaptive strategies remains unclear ...