Glassy dynamics model predicts lipid exchange rates across cell membranes

Biological processes that govern our lives are many, intertwined, and often difficult to understand. They involve countless ...

Cryo-EM structures reveal conformational dynamics behind AP-4 membrane trafficking

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...
Labmate Online

Cell membrane thickness measured inside living cells for first time; Scripps method reveals hidden variations

A Scripps team has adapted advanced imaging and computation to measure cell membrane thickness inside intact animal and yeast ...
GEN

First Vascularized Organoid Model of Stem Cell-Derived Pancreatic Islets

An international team of researchers led by Max Delbrück Center Scientific Director Professor Maike Sander, MD, has for the first time developed an organoid model of human pluripotent stem ...
GEN

Generative AI Model, ChromoGen, Rapidly Predicts Single-Cell Chromatin Conformations

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...
ascopubs.org

Deep-Learning Model for Real-Time Prediction of Recurrence in Early-Stage Non–Small Cell Lung Cancer: A Multimodal Approach (RADAR CARE Study)

Physiologically Based Pharmacokinetic Model to Assess the Drug-Drug-Gene Interaction Potential of Belzutifan in Combination With Cyclin-Dependent Kinase 4/6 Inhibitors A total of 14,177 patients were ...
Phys.org

The mechanical ratchet: A new mechanism of cell division

Cell division is an essential process for all life on Earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive—particularly for egg-laying species ...