Most forms of apoptosis involve caspases, the proteases that are activated by apoptotic signals to digest cellular proteins and induce death. 1,2 Caspases are cysteine-dependent proteases that ...

Despite extensive use over 40 years, physical activity questionnaires still show limited reliability and validity. Measurements have value in indicating conditions where an increase in physical ...

Understanding the function and behavior of enzymes in various biological processes is essential to numerous scientific sectors, including pharmaceuticals, food, and chemical industries. As the ...

Lupus disease complexity and variability makes accurate measurement of disease activity very challenging. Measurement of disease activity in lupus is central to clinical research and clinical trials ...

In the past several decades more than 30 new treatments for lupus have failed in clinical trials, even though all had seemed promising in the test tube. These repeated failures take a toll on the ...