Intracellular peptide signalling represents an emerging paradigm in neurobiology, in which short peptide fragments generated by proteasomal degradation or specific endopeptidases act as bioactive ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

Scientists have discovered novel molecular mechanisms that contribute to recovery from diabetic kidney disease following bariatric surgery in adolescents with type 2 diabetes and obesity, mechanisms ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

Hexarelin is a synthetic hexapeptide that emerged from late-20th-century efforts to design growth hormone–releasing peptides ...