When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain. The resulting ...

These intercellular messages, ferried about by molecules called interferons, serve as a warning signal to nearby cells—“‘You are about to be infected; it’s time for you to set up an antiviral state,’” ...

Bonn, November 8, 2022 - The innate immune system fights infectious agents. The alarm messenger interferon plays a central role in this. However, if it is produced in the absence of an infection, it ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

When pathogens attack the body, the innate immune system goes to work protecting against the invading disease. The innate immune system is the first line of defense. It detects precisely what the ...