Imagine, if you dare, a world without P values. Perhaps you’re already among the lucky participants in the human race who don’t know what a P value is. Trust me, you don’t want to. P stands for ...

Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

Michael Lew has received funding from the NHMRC. Yesterday’s article by Geoff Cumming, based on a very recent Proceedings of the National Academy of Science paper, argued that “null hypothesis ...

It is of fundamental interest in statistics to test the significance of a set of covariates. For example, in genomewide association studies, a joint null hypothesis of no genetic effect is tested for ...

Suggested Citation: "Appendix D: Using Bayes Analysis for Hypothesis Testing." National Academies of Sciences, Engineering, and Medicine. 2019. Reproducibility and ...