PAX6-dependent epithelial differentiation and developmental trajectories of the ocular surface are elucidated through single-cell RNA sequencing of hiPSC-derived ocular organoids. This study provides ...

Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why ...

A recent Nature study evaluates post-implantation development in humans using embryo-like models based on genetically unmodified human naïve embryonic stem cells (ESCs). Study: Complete human day 14 ...

Animal models continue to be a mainstay of basic research and preclinical studies. But since animals such as mice only approximate humans, they may generate findings of limited clinical relevance.

Researchers have used stem cells to develop new human embryolike structures that model the earliest stages of fetal development so realistically that they even secrete hormones that can turn a lab ...

The world has now learned of a surprising scientific advance: so-called “synthetic embryos.” Their arrival promises to reveal to medicine previously hidden glimpses into problems of early pregnancy.

Scientists reveal unprecedented insights into human limb development, including the many intricate processes that govern their formation. Human fingers and toes do not grow outward; instead, they form ...

Neuroscientists have been trying to understand how the brain processes visual information for over a century. The development of computational models inspired by the brain's layered organization, also ...