The majority of human illnesses is caused by damage of a single organ like the liver whose failure accounts for 2M deaths worldwide every year. Orthotopic transplants are the only curative therapy ...

The human liver plays a pivotal role in drug metabolism, largely attributable to the diverse family of UDP-glucuronosyltransferases (UGTs) that catalyse glucuronidation reactions. This conjugation ...

Surgeons have now published the first report of a gene-edited pig liver transplanted into a person. The liver, which came from a genetically modified pig, appeared to stay active, producing bile and ...

A multidisciplinary team from China has successfully transplanted a gene-modified pig liver into a human recipient diagnosed with brain death. During a 10-day observation period, the porcine liver ...

Scientists from Cincinnati Children’s Hospital Medical Center and their collaborators have used human stem cells to develop liver organoids that faithfully replicate key zones observed in human livers ...

Chinese researchers are reporting new steps in the quest for animal-to-human organ transplants — with a successful pig kidney transplant and a hint Wednesday that pig livers might eventually be useful ...

Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have helped to understand liver biology, they often fail to accurately ...

Scientists from Cincinnati Children's and colleagues based in Japan report achieving a major step forward in organoid technology: producing liver tissue that grows its own internal blood vessels. This ...

The liver came from a genetically modified cloned pig with ten gene edits. Pexels For the first time, surgeons have grafted part of a liver from a genetically modified pig onto a human patient’s organ ...

For the first time, researchers have successfully connected a functioning liver from a genetically modified pig to a human body.* In a step toward testing the procedure in living people, a team at the ...

Laura holds a Master's in Experimental Neuroscience and a Bachelor's in Biology from Imperial College London. Her areas of expertise include health, medicine, psychology, and neuroscience. Laura holds ...