The hot melt extrusion (HME) process can be employed in the production of a wide range of pharmaceutical dosage forms, including capsules, tablets, lozenges and implants. HME is suitable for both ...

Thanks to their safety, ease of application and ability to administer a precise dose of an active pharmaceutical ingredient (API), orally disintegrating films make an appealing method of dosage. The ...

PTE: One tool for bioavailability enhancement is to create amorphous solid dispersions through processes such as hot-melt extrusion (HME) or spray drying. What factors come into play to decide whether ...

How does hot melt extrusion complement Quality by Design? With an increasing focus on Quality by Design (QbD), pharmaceutical companies need to be able to control and analyse product quality online ...

Accurate prediction of breakthrough extruding force is very important for extrusion production, especially for the large-scale extrusion process, which directly affects the production costs and safety ...