Histone post-translational modifications (PTMs) comprise one of the most intricate nuclear signaling networks that govern gene expression in a long-term and dynamic fashion. These PTMs are considered ...
DNA interaction could unlock targeted therapeuticsDid you know that every cell in our body has the same DNA inside ...
Histones are perhaps more intimately linked with DNA than any other protein. Transcriptional regulation, recombination, repair, and replication--basically anything that happens to the DNA--must happen ...
In a recent study published in the journal Science Advances, a group of researchers investigated the role of histone modifications in human aging by developing and evaluating histone-specific age ...
1 Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA 2 Department of Chemistry, Princeton University, Princeton, NJ 08544, USA Histone post-translational modifications ...