MPN-BP transformation is driven by sequential mutations disrupting genomic stability, with TP53 mutations being strong predictors of progression. TP53 mutations confer a selective growth advantage, ...

The genetic code acts as life’s instruction manual, telling cells how to build proteins from DNA and RNA. Though it's a marvel of molecular precision, the path it took to evolve remains unclear. Fresh ...

Researchers at the University of Maine are theorizing that human beings may be in the midst of a major evolutionary shift—driven not by genes, but by culture. "Human evolution seems to be changing ...

The present theory offers a unified solution to three closely related evolutionary problems. (1) Why does an evolving population explore only a small fraction of the accessible pathways in genotype ...