Study reveals how aging accelerates molecular changes in the brain, offering new hope for tackling cognitive decline and mental illness. Resource: Single-nucleus transcriptomic profiling of human ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

Summary: A team of investigators from Dana-Farber Cancer Institute, The Broad Institute of MIT and Harvard, Google, and Columbia University have created an artificial intelligence model that can ...

New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Transcriptional regulation is a fundamental biological process where proteins interact with deoxyribonucleic acid (DNA) to ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Researchers have developed a new computational approach that uncovers possible drugs for specific cellular targets for ...

The Joint Open Genome and Omics Platform 1.0 (JoGo 1.0) catalogs 19,194 human genes with a novel naming system. Researchers expect the database to benefit medicine and genomics, and to provide a ...