Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...

The protein community is awash in data. As of October, the UniProt database of protein sequences had more than 44 million entries. UniProt serves as a clearinghouse for sequences. Researchers who ...

It has been known in biology for a long time that the excited oxygen molecule singlet oxygen is the main cause of aging in cells. To counter this, nature uses an enzyme called superoxide dismutase to ...

A new technique could make it easier to target and inhibit specific enzymes and other proteins in cells and to turn that regulation on and off at will with light. The approach provides researchers ...

Ensemble map of protein structure. The team’s approach integrates different NMR data to create a map of how different parts of a molecular structure move. Tokyo, Japan – Researchers from Tokyo ...

Just because an enzyme has an active site doesn’t mean the rest of the enzyme should be disregarded, as though it were so much dead weight. It influences enzyme function, if only by keeping the enzyme ...

Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...

Scientists have discovered a new function in a plant enzyme that could inspire the design of new chemical catalysts. The enzyme catalyzes, or initiates, one of the cornerstone chemical reactions ...

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

A research team at Leibniz-HKI has described a new enzyme that renders the highly toxic molecule malleicyprol harmless.