Modified Toxicity Probability Interval Design: A Safer and More Reliable Method Than the 3 + 3 Design for Practical Phase I Trials. If you have the appropriate software installed, you can download ...

This third installment in the golf putter design series moves the process from reverse engineering and additive manufacturing to CAD/CAM software. Turning attention to the role of CAD/CAM software in ...

The product development process can be improved with single-physics simulation, multiphysics simulation and simulation apps. This article looks at three real-world examples that show how integrating ...

After a long 18 months of negotiations and regulatory scrutiny, Synopsys has finalized its approximate $35 billion acquisition of Ansys. This acquisition merges two leading companies in their ...

Simulation is playing an increasingly critical and central role throughout the design-through-manufacturing flow, fusing together everything from design to manufacturing and test in order to reduce ...

The 3 + 3 design is the most common choice among clinicians for phase I dose-escalation oncology trials. In recent reviews, more than 95% of phase I trials have been based on the 3 + 3 design. Given ...