A team has unlocked a decades old mystery about how a critical cellular process called DNA replication is regulated. A team of Florida State University researchers has unlocked a decades-old mystery ...

Unlike nuclear DNA, mitochondrial DNA (mtDNA) is circular in nature and organized as mitochondrial nucleoids comprised of DNA-protein complexes that are distributed in the matrix. It is also inherited ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

DNA over-replication is a phenomenon that can have devastating consequences for proliferating cells. When parts of the genome are duplicated more than once, cells suffer from 'genomic instability' ...

Undergraduate biology students could be forgiven for thinking that scientists have DNA replication all figured out. After all, textbooks present the models of replication so matter-of-factly that it's ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...