Aim: To demonstrate the potential of in-line nanoparticle size measurements using the NanoFlowSizer (NFS) as a PAT method. To achieve real-time process control by establishing automated regulation of ...

Technological innovations throughout the past several decades have transformed the pharmaceutical manufacturing process from traditional batch production to ...

Anything that you do well is worth doing better over time. The term "continuous improvement" describes a process practiced by quality engineers but it speaks to something that every conscientious ...

This article overviews some of the benefits and methods of state-based control as it applies to the models defined by the ISA106, Procedure Automation for Continuous Process Operations standards ...

Advances in process analytical technology have been achieved, but significant challenges remain. Continuous API manufacturing has the potential to provide tremendous benefits to the pharmaceutical ...

Advances in equipment, instrument, and control systems are enabling online monitoring of continuous API manufacturing. Continuous API manufacturing has the potential to provide tremendous benefits to ...

Methods to Simultaneously Reduce Bioburden and Maintain Column Integrity, Explained Continuous bioprocessing is inevitably becoming the future of biomanufacturing. To date, several steps within a ...

The extent to which products meet specifications needs to be systematically monitored in a production process. Product quality will typically be defined by two quantities: deviations from stated ...