People have recognized the promise of continuous manufacturing processes ever since Henry Ford’s auto assembly line kicked into action. Even so, pharmaceuticals are still made in batches. Proponents ...
Research efforts around the world are demonstrating that the application of flow chemistry for small-molecule API synthesis. Continuous flow manufacturing for small-molecule drug synthesis received a ...
High-temperature, short-time (HTST) pasteurization and ultra-high temperature (UHT) sterilization are potentially useful as part of the trend toward methods of continuous manufacturing of ...
In conventional centrifugation rotors, material processing involves a number of tedious steps, which need to be repeated until the whole sample has been processed. If the amount of material to be ...
A photo of technicians working in front of a process train. Novartis's continuous manufacturing center in Basel, Switzerland, replicates an end-to-end manufacturing process developed at the ...
The use of left ventricular assist devices is an accepted therapy for patients with refractory heart failure, but current pulsatile volume-displacement devices have limitations (including large pump ...