Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

From single DNA letter swaps to hidden non-coding tweaks, mutations can rewire how our bodies work—sometimes in life-changing ways. Scientists are uncovering how these changes influence protein ...

Study lead Associate Professor Elisa De Franco, of the University of Exeter Medical School, said, "For the first time, we found that DNA changes in non-protein coding genes cause neonatal diabetes.

Researchers announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

Learn how small mutations in non-coding DNA can alter sex development in rodents.

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

For decades, scientists have been puzzled by large portions of the human genome labeled as “junk” DNA, sequences that seemingly serve no purpose. Yet, recent studies suggest these cryptic sequences ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

Scientists have uncovered new genetic causes of diabetes in infants, pointing to a region of the genome that has long been ...