The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Study lead Associate Professor Elisa De Franco, of the University of Exeter Medical School, said, "For the first time, we found that DNA changes in non-protein coding genes cause neonatal diabetes.

Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize ...

Image Caption: Technologies evolved related to the Human Genome Project. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on ...

A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or so-called 'junk' DNA—includes many of the "switches" that control when and ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...