Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...
Scientists first observed the biological phenomenon of restriction and modification in the 1950s, but they did not identify and isolate restriction enzymes until the late 1960s. 3 In 1970, Hamilton ...
A team led by investigators has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies. A team led by investigators at Massachusetts General Hospital (MGH ...
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