The G2 checkpoint monitors DNA damage, preventing mitotic entry until the damage can be resolved. The mechanisms controlling checkpoint recovery are unclear. Here, we identify non-genetic ...
The Cdc25 phosphatases (Cdc25A, B and C) regulate eukaryotic cell-cycle progression through the dephosphorylation and activation of their substrates, the CDK–cyclin complexes (Boutros et al., 2006).
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