Understanding the link between nucleotide metabolism and chromatin assembly

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...
Technology Networks

Critical Coordinator of DNA Repair During Cell Division Identified

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...
eLife

Replication stress-inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis in luminal progenitors

ELF3 axis enables luminal progenitor transformation in BRCA1-deficient breast cancer by reducing genomic instability and promoting progenitor identity.
EurekAlert!

Engineered RNA sensor detects and fights coronavirus inside living cells

A research team has developed a new RNA-based system that can detect coronavirus infection in real time inside living cells—and even trigger antiviral responses only when infection occurs.
AZoLifeSciences on MSN

Synthetic RNA platform converts viral replication into detectable cellular signals

The technology, called the Viral-Engineered RNA-based Activation System (VERAS), hijacks the virus's own replication ...
Hosted on MSN

Q&A: Why it's important for cells to make copies on an exacting schedule

Allison McClure, Ph.D., is an assistant professor in the Department of Biochemistry and Molecular Genetics at the CU School of Medicine. She is focused on learning all about how cells replicate, or ...