All living things polarize, so examining the elements of how this occurs is to study the basic necessities of life. Lombardo’s lab focuses on studying human cell polarity and was recently awarded a ...

Planar cell polarity (PCP) mechanisms orchestrate the uniform orientation of cells within the plane of a tissue, playing a pivotal role in embryonic development, tissue organisation and the ...

Epithelial tissues define organ boundaries and perform selective barrier, transport and signalling functions. Their formation relies on the orchestration of cell polarisation, coordinated shape ...

Scientists have uncovered a key mechanism in jellyfish embryos that provides new insights into how the body plan of these animals develops along a central axis from their ‘head’ to ‘tail’. The study, ...

Dr. Irwin Arias, emeritus senior scientist at the National Institutes of Health (NIH) and a renowned doctor in the field of hepatology, the study of the liver, emphasized the importance of studying ...

A team led by Prof. WANG Chao and Prof. HUANG Chengdong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) revealed the molecular mechanism of ...

Cold Spring Harbor Laboratory Press (CSHLP) announced the release of Cell Polarity, available on its website in hardcover format. Most animal cells are polarized, with structurally and functionally ...

Mentor: Yoshinori Tomoyasu, Ph.D. Planar Cell Polarity is crucial for the development and functions of many tissues and organs. The mechanism of planar polarity characterizes the coordination and ...

Preventing metastasis—the development of cancer cells beyond their original location—remains one of the major goals of current cancer research. Most malignant tumor cells metastasize by exploiting ...