Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins. When molecules of a drug ...

Cell membranes protect and organize cells. All cells have an outer plasma membrane that regulates not only what enters the cell, but also how much of any given substance comes in. Unlike prokaryotes, ...

Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell and its environment. However, evidence has recently emerged suggesting that these membranes do ...

HIV-1 remodels the spatial organization of its co-receptor, CXCR4, on T cell membranes, showing that viral entry requires receptor clustering rather than simple receptor binding.

Our skin and mucous membranes are protected by epithelial cells. This barrier tissue performs its function thanks to specialized structures called junctions. They ensure cell cohesion and regulate ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital, published in Cell, ...

An enduring challenge for the commercialization of genetic therapies is delivering the therapeutic molecules to the proper destination within the body. Viruses are natural delivery systems for nucleic ...

FUJIFILM Corporation announced today that it has developed an innovative screening methodology for cyclic peptides exhibiting high affinity toward membrane proteins1. This new technology enables ...

Impaired mitophagy and the accumulation of damaged mitochondria are key drivers of endothelial cell (EC)dysfunction in ...