For the first time, scientists have answered a longstanding question in cell biology about a partnership of proteins called ...

Recent research has identified a specific biological mechanism that may explain why females experience more severe ...

A giant functional atlas of immune cells in a Chinese cohort reveals crucial differences with European and Japanese data sets ...

Randomness inside cells can decide whether a cancer returns after chemotherapy or whether an infection survives antibiotics.

Cancer therapy and synthetic biology are converging around a shared problem that has long frustrated oncologists and ...

PKM2 acts like a switch for cellular energy, directly determining whether cancer cells can rapidly generate energy and biosynthetic precursors to support their continued growth. Using a driving ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

Cell division is an essential process for all life on earth, yet the exact mechanisms by which cells divide during early ...

The FDA approval of denileukin diftitox (Lymphir) marked a significant shift in this paradigm. As a first-in-class immunotoxin, it employs a dual-action mechanism: directly targeting interleukin-2 (IL ...

Spatial proteomics is the study of the spatial distribution of the proteins within cells and tissues. The subcellular localization of proteins is intrinsic to cellular function, making spatial ...

Biology has always been an unruly science. Cells divide when they want to. Genes switch on and off like temperamental lights.