Cells in the human body accumulate cancer-promoting mutations throughout their lifespan, yet these mutations rarely drive tumour formation. Tumours in a given tissue usually originate from a specific ...
New research from Dana-Farber Cancer Institute shows that a new class of drug results in cell death in cancers, such as small cell lung cancer, with a disabled quality control cell cycle checkpoint ...
The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...
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