Breast cancer study reveals synergistic effect of CDK2 and CDK4/6 combination therapy

A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published in Nature ...

Tiny molecules called tRNA halves may contribute to prostate cancer cell growth

Prostate cancer is the second-most common cancer in men. A new study from Thomas Jefferson University uncovered a new ...

Super-enhancers in cancer cells trigger DNA breaks and error-prone repair cycles

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...
University of California

New vulnerability identified in aggressive breast cancer

By targeting proteins used to splice genes, UC San Diego researchers have unlocked a new approach to treating triple-negative ...
Frontiers

Combination Therapies in Cancer Treatment: Enhancing Efficacy and Reducing Resistance

Combination therapies represent a promising frontier in cancer treatment, addressing the critical need to enhance efficacy while minimizing resistance. By combining different therapeutic agents and ...
EurekAlert!

Centromere protein I, a cell cycle checkpoint gene, accelerates tumor progression via the hippo pathway and mediates immune escape in hepatocellular carcinoma

Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma ...

Active aldehydes drive T cell exhaustion in the tumor microenvironment, finds study

Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...
Frontiers

Cuproptosis in Cancer: Mechanisms, Microenvironment, and Therapeutic Exploitation

The field of regulated cell death has undergone a transformative shift with the discovery of novel modalities beyond apoptosis, such as ferroptosis, which ...