New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Please provide your email address to receive an email when new articles are posted on . An ongoing study showed improvements in SSc severity, disease-related pain, Raynaud’s symptoms and ...

Researchers headed by a team at New York University (NYU) College of Dentistry’s Pain Research Center have identified a compound, designated CBD3063, that in animal studies reversed four types of ...

Hand opening pill bottle Clearer guidelines for diuretic management in patients with chronic kidney disease are needed, according to investigators. Adding diuretics rather than calcium channel ...

Little additional work has been performed beyond that of Lee et al. [1,3,10] to further investigate the proposed dual action of ibutilide. Our laboratory has sought to examine the effects of sodium ...

Voltage‐gated calcium channels, particularly the CaV2.1 channels encoded by the CACNA1A gene, are central to cerebellar function and synaptic transmission. Dysfunction in these channels leads to a ...

A woman with hopes to conceive was diagnosed with severe vasospastic angina (VSA); however, she was able to carry a healthy baby to full term without angina attacks after starting treatment of a ...

Please provide your email address to receive an email when new articles are posted on . Beta-blockers more effectively reduce risk for death or hospitalization in people with HFpEF compared with ...

A woman with hopes to conceive was diagnosed with severe vasospastic angina (VSA); however, she was able to carry a healthy baby to full term without angina attacks after starting treatment of a ...

Examining data on more than 400,000 participants in the U.K. Biobank revealed that use of CCBs was associated with a 39% greater odds of glaucoma after adjusting for various factors, including the use ...

An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study. Targeting this protein -- the ORAI1 calcium ...