Bone tissue engineering and regeneration stands at the forefront of regenerative medicine, offering innovative solutions for skeletal repair and reconstruction. This multidisciplinary field integrates ...
Drug trial shows reduced abnormal bone formation in those with fibrodysplasia ossificans progressiva
A multisite, international phase 2 trial evaluating the investigational drug garetosmab has shown that it reduced soft-tissue flare-ups significantly and prevented new areas of abnormal bone formation ...
Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from the Institute of Science Tokyo, Japan. Hypoxic conditions ...
Osteocytes, the most abundant cells in bone tissue, have long been underestimated in their functional capacity. Traditionally viewed as passive entities, recent research has illuminated their pivotal ...
Bone implants often fail to fully integrate with surrounding tissue, limiting their effectiveness in regeneration. A natural but often overlooked cellular process could hold the key to better outcomes ...
A new small molecule could treat and prevent excess bone formation. Fibrodysplasia ossificans progressiva (FOP) is an extremely rare disease estimated to affect about one in 2 million people worldwide ...
Scientists uncovered how the protein Piezo1 translates physical activity into stronger bones, offering a path to exercise-mimicking therapies. Scientists from the Department of Medicine, School of ...
The field of bone tissue engineering (BTE) was a promising avenue for addressing bone injuries and defects by constructing artificial scaffolds with bionic functionalities. Due to its unique 3D ...
A recent discovery could transform our understanding of bone health maintenance and pave the way for potential treatments for bone diseases, including osteoporosis. Researchers at the University of ...
A recent discovery could transform our understanding of bone health maintenance and pave the way for potential treatments for bone diseases, including osteoporosis. Researchers at the University of ...
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