Diabetes mellitus has emerged as a critical factor influencing male reproductive health in animal models, with sustained hyperglycaemia leading to a spectrum of testicular dysfunctions. Experimental ...

Animal models continue to be a mainstay of basic research and preclinical studies. But since animals such as mice only approximate humans, they may generate findings of limited clinical relevance.

LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...